Here’s How it Works in the Brain and Body
Before I get stuck into the details of CBD for pets, here’s a quick crash-course in CBD for those of you reading who aren’t too familiar with how this compound works.
CBD, as you probably know, is a non-intoxicating cannabinoid found in cannabis and hemp.
Like other cannabinoids, CBD interacts with your body’s endocannabinoid system.
How it does so, however, is very different from other cannabinoids.
THC, for example, works by binding directly to cannabinoid receptors CB1 in the brain and body.
When it does so, the endocannabinoid system begins to down-regulate, which can affect the way the body responds to stress, alter appetite and energy levels, promote changes in metabolism, and much more.
CBD, however, doesn’t have a high binding affinity for either cannabinoid receptor.
Instead, it seems to act on a variety of other receptors, including those for neurotransmitters like serotonin, gamma, GABA, and more.
In fact, studies have identified over 60 different molecular pathways that are affected by CBD.
Studies also show that CBD can inhibit a process known as reuptake and thereby temporarily increase the levels of some chemicals (such as endocannabinoids) in the brain.
So, How Does CBD Affect Dogs?
Dogs have an endocannabinoid system just like humans do.
In fact, many mammals (including dogs, cats, horses, mice, and rats) have endocannabinoid systems which seem to work similarly to the human endocannabinoid system.
Today, there’s even a growing body of pet owners who are seeing great results using